Our mission is to save lives by promoting prompt diagnosis and raising awareness of the classic symptoms of an infection that triggers the heart disease, the leading cause of pediatric heart conditions in the developing world.
The fund aims to raise money and awareness about Kawasaki Disease, which mainly affects children younger than five-years-old with symptoms including fevers, eye infections and rashes.
The founder is passionate about fighting the disease after doctors repeatedly failed to spot the symptoms in her daughter Nadia when she was only seven months old in 1993.
After a diagnosis and a full recovery three years later, the mother-daughter pair now fight the disease together with events such as the creative workshop.
Dee Izmail said: “People should come along if they have got creative skills they would like to express, it is a great opportunity for an open and professional workshop.”
Founder Dee Izmail and her team work to get a better understanding of KD and spread knowledge through creative Campaigns and Events. Collaborating with potential sponsors in all sectors will help utilise extensive charity workspace in Essex & London with Partners who create new revenue streams and donations for the charity cause.
The team aims to support and gain updated research with specialists and research departments to develop awareness in communities.
Mission: To save lives and promote recovery in those who acquire heart disease (KD).
Vision: We want to see more occurrences of early detection of symptoms, and the right treatment before problems occur in adult life. Together we will make it happen.
Kawasaki Disease is also called Kawasaki Syndrome or mucocutaneous lymph node syndrome. The illness was first described in Japan by Dr Kawasaki in 1967. It is an illness mainly affecting children under five. It is characterised by inflammation of the blood vessels (‘vasculitis’) and in particular damages the coronary arteries that supply blood to the heart. About 1/3 of untreated children with KD suffer heart damage, making it the most common cause of heart disease acquired in childhood in many countries, including the UK.
The cause of KD remains unknown, but is believed to be due to an infection that all children get in early childhood and to which a minority of children react abnormally. There is good evidence to suggest that these children have an inherited predisposition to KD (and also to developing heart damage once they have KD). Projects therefore investigate the genes controlling the immune system that may be important in determining susceptibility and heart damage. This will tell us not only about the cause of KD, but may also help understand the basis of ischaemic heart disease in adults (heart attacks, angina etc).
KD is a model in which to study the role of infection in damaging blood vessels and developing atherosclerosis. Kawasaki Disease appears to run a triphasic course. The first phase is seen during the first 8-12 days and the child exhibits a fever with mouth and skin changes. The child appears acutely ill and may at this stage show signs of aseptic meningitis, loose stools and jaundice. Towards the end of this phase the child may show great improvement and existing symptoms may resolve. The sub-acute phase two occurs 6-10 weeks after onset of fever. This is characterised by peeling skin at the the hands and feet, mood changes, loss of appetite and possible cardiac and joint involvement. For children to be diagnosed as having the disease, other disorders that might mimic the condition must be excluded.
5/6 criteria must be satisfied:
- Fever persisting over five days
- Conjunctival eye infection
- Changes in the mouth. Reddening and crusting of lips, diffuse or oropharyrn geal (redness in back of the mouth), erythematic (skin redness), strawberry tongue.
- Changes in extremities of hands and feet, erythema of palms and toes, peeling of finger/toe tips (two weeks after fever onset), crosswise grooves across finger nails (two or three months after onset).
- Erythemoutous rash (skin redness)
- Enlarged lymph nodes
Watch this space for key updates and publications: -
- Australian Family Physician
- The Royal Children’s Hospital
- Archive of Disease in Childhood 2015
If you experience difficulty accessing journals please let us know so we can grant access.
More from ADC
- Technology and Tools We saw this and hope more doctors will make use of technology and tools like VisualDx so fewer cases of KD go misdiagnosed. This shows how difficult it can be for doctors to diagnose. “It’s one of those conditions where, if you’re not thinking of it, you’ll miss it. Doctors will say, ‘It’s a virus. It’ll pass’, but it’s one of the few conditions where kids can die of a major heart attack”.
Podium Creative Enterprise Ltd.